Homolog.us is an amazing site. The content is clear, rich and very entertaining (at least for those who like biology and technology). They have an active Twitter account, they answer comments, they are on reddit too. These guys rock!
Recently they wrote about PacBioToCA, pointing out its lengthy execution. It’s common in biotechnology parallel execution with OpenMPI, OpenMP or other method like MapReduce.
One idea would be review the code, check if it’s doable some kind of parallelism and write about it. Perhaps rewriting it. They already wrote about another tool that competes with PacBioToCA. I told you that Homolog.us is amazing.